Background: There is bound data on the prevalence of impulse control disorder and related behaviors (ICD-RBs) in Indian patients with Parkinson’s Disease (PD). (8.4%), compulsive medication use (7.7%), compulsive eating (5.35%), walkabout (4%) and pathological gambling (3.3%). 2 ICD-RBs were observed in 15.7% of patients. After multivariate analysis, younger age of onset, being unmarried were specifically associated with presence of ICD. Longer disease duration was specifically associated with presence of ICRB. Whereas smoking and higher dopamine levodopa equivalent daily doses (DA LEDD) were associated with both presence of ICD and ICRB. Higher LD LEDD was specifically associated with presence of ICD-RB. Conclusions: Our study revealed a relatively higher frequency of ICD-RBs, probably because of the use of screening instrument and because we combined both ICRBs and ICDs. Also high percentage of DA make use of (81.6%) among our individuals may be responsible. The part of genetic elements that might boost the threat of developing ICD-RBs with this inhabitants wants further exploration. < 0.1) association with ICD-RBs on bivariate evaluation were contained in a multivariate Ki16425 logistic regression model, examining for individual predictors of ICD-RB like a binary reliant variable. The outcomes had been reported as OR (95% CI). The P-value significantly less than 0.05 was considered significant statistically. Outcomes Explanation of research inhabitants Total 299 individuals participated in the scholarly research. Almost all individuals, = 296 (98.9%) were acquiring either LD or DA. Most individuals, = 245 (81.9%) had been on DA, 100 individuals (33.4%) were on DA monotherapy. 146 individuals (50.3%) were about pramipexole and 101 individuals (34.8%) had been on ropinirole. 196 individuals (65.5%) had been on LD, 51 individuals (17.1%) had been about LD monotherapy. 145 individuals (48.5%) had been on both LD and DA. The mean (SD) LEDD, mg for LD was 460.5 (277.3), for DA: 235 (160), for pramipexole: 305 (150) as well as for ropinirole: 130 (100). The mean (SD) total LEED, mg was 698 (406). Notice is constructed of designated difference in mean LEDD of pramipexole and ropinirole [Desk 1]. Desk 1 Demographic, medical and treatment features of all research topics Prevalence of Impulse control disorders and related behaviors At least Ki16425 one ICD-RB was within 128 (42.8%), at least one ICD was within 74 (24.75%) with least one ICRB was within 93 (31.1%) individuals. Punding was the most typical (12.4%) accompanied by hyper sexuality (11.04%), compulsive hobbyism (9.4%), compulsive buying (8.4%), compulsive medicine make use of (7.7%), compulsive feeding on (5.35%), walkabout (4%) and pathological gaming (3.3%). 2 ICD-RBs had been seen in 15.7% of individuals. The rate of recurrence of ICD-RBs in topics exposed and then LD (20.3%) was less than in those about DA agonists monotherapy (24.2%), which was less than in those subjected to both LD and DA agonists (55.5%) [Desk 2]. Desk Ki16425 2 Prevalence of Impulse control disorders and related behaviors Demographic, medical & treatment features of subgroups on basis of existence or lack of ICD-RBs According to bivariate evaluation, compared with patients without ICD-RBs, those with ICD-RBs had younger age at disease onset, were more likely to be unmarried, smokers, taking alcohol, having longer disease duration. Regarding treatment characteristics: Patients taking LD, DA, entacapone and amantadine had a higher frequency of ICD-RBs. Also, compared with patients without ICD-RBs, those with ICD-RBs were on higher dose and longer treatment duration of LD and DA [Table 3]. Table 3 Demographic, clinical and treatment characteristics of all study subjects and of subgroups on basis of presence or absence of ICD-RBs Demographic, clinical & treatment characteristics of subgroups on basis of presence or absence of ICDs As per bivariate analysis, compared with patients without ICDs, those with ICDs had younger age at time study and at disease onset, were more likely to be unmarried, smokers, taking alcohol, having longer disease duration. Regarding treatment characteristics: patients taking DA and amantadine had a higher frequency of ICDs. Also, compared with patients without ICDs, those with ICDs were on higher dose and longer treatment duration of DA [Table 4]. Table 4 Demographic, clinical and treatment characteristics of all scholarly study subjects FGF6 and of subgroups in basis of presence or absence.